Down’s syndrome including early detection of complications in pregnancy
Complications of pregnancy are health problems that occur during pregnancy. They can involve the mother’s health, the baby’s health, or both. Some women have health problems before they become pregnant that could lead to complications. Other problems arise during the pregnancy.
Pregnancy disorders and complications are poorly predicted by traditional risk factors and maternal history alone. By combining this information with biomarker testing using risk calculation software, complications in pregnancy can be detected early and it also reduces unnecessary invasive tests.
Biomarkers, or biological markers, are a non-invasive pre-natal screening method. Biomarkers measured in the first trimester of pregnancy can predict the incidence and severity of disease allowing for improved and targeted prophylactic therapies to prevent adverse maternal and fetal outcomes.
Traditionally biomarkers have been used as pre-natal screening in the first and second trimester of pregnancy to identify Trisomy 21 or Down’s syndrome. However, non-invasive first trimester screening provides the possibility to predict so much more than only fetal aneuploidies. In addition to the risk assessment for aneuploidies, biomarkers can be used to screen for other conditions, such as pre-eclampsia, fetal growth restriction and preterm birth.
- Gestational diabetes
- Preterm delivery
- Open spina bifida
- Major cardiac defects
- Small for gestational age
- Trisomy 21, 18 and 13
Humor Diagnostica offers biomarkers for the first and second trimester non-invasive screening of mother and baby on the BRAHMS Kryptor analyzer. For more information on these biomarkers, free βhCG, PAPP-A, hCG+β, AFP and uE3, please download the product information brochure below.
Download the product information brochure here: